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Cannabis, also known as marijuana (Spanish pronunciation: [maɾiˈwana]) among other names,^[a] is a psychoactive drug from the Cannabis plant used primarily for medical or recreational purposes.^[18][19][20] The main psychoactive component of cannabis is tetrahydrocannabinol (THC), which is one of the 483 known compounds in the plant,^[21] including at least 65 other cannabinoids,^[22] including cannabidiol (CBD).^[23] Cannabis can be used by smoking, vaporizing, within food, or as an extract.^[24]

Cannabis has various mental and physical effects, which include euphoria, altered states of mind and sense of time, difficulty concentrating, impaired short-term memory and body movement,^[24] relaxation,^[25] and an increase in appetite.^[26] Onset of effects is felt within minutes when smoked, and about 30 to 60 minutes when cooked and eaten.^[24][27] The effects last for two to six hours, depending on the amount used.^[27] At high doses, mental effects can include anxiety, delusions (including ideas of reference), hallucinations, panic, paranoia, and psychosis.^[24][23] There is a strong relation between cannabis use and the risk of psychosis,^[28][29] though the direction of causality is debated.^[30] Physical effects include increased heart rate, difficulty breathing, nausea, and behavioral problems in children whose mothers used cannabis during pregnancy;^[24] short-term side effects may also include dry mouth and red eyes.^[31][32] Long-term adverse effects may include addiction, decreased mental ability in those who started regular use as adolescents, chronic coughing, and susceptibility to respiratory infections.

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